Q: What is GABA?
Gamma-aminobutyric acid (GABA) is a principal neurotransmitter in the brain and central nervous system involved in a calm response to stress. It influences the parasympathetic nervous system, which is responsible for the relaxing “rest and digest” state, as opposed to the “fight or flight” feelings of agitation and anxiety induced by the sympathetic nervous system.
GABA is naturally synthesized from the amino acid glutamate, but some individuals may benefit from supplemental amounts. While glutamate is an “excitatory” neurotransmitter, GABA is inhibitory, which helps to balance the stimulating effects of glutamate. GABA slows down the activity of nerve cells and helps prevent them from over-firing. Through this mechanism, GABA serves as a calming agent for the body, helping to combat occasional stress, restlessness and nervous irritability. Keeping GABA levels optimal may help support balanced moods and a healthy response to stressful situations.*
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